Overeating Triggers Molecular ‘Firing Squad’ In Mice, Destroys Metabolism
February 6th, 2010 admin
Overeating in mice triggers a molecule once considered to be only involved in detecting and fighting viruses to also destroy normal metabolism, leading to insulin resistance and setting the stage for diabetes…
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Overeating in mice triggers a molecule once considered to be only involved in detecting and fighting viruses to also destroy normal metabolism, leading to insulin resistance and setting the stage for diabetes…
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Mice that are missing a protein involved in the response to low oxygen stay lean and healthy, even on a high-fat diet, a new study has found. “They process fat differently,” said Randall Johnson, professor of biology at the University of California, San Diego, who directed the research, which is published in the April 15 issue of the journal...
When researchers created mice lacking an enzyme that breaks down and releases stored triglycerides (more properly known as triacylglycerols or TGs), they expected to see animals with better lipid profiles. But according to a report in the March Cell Metabolism, a Cell Press publication, they got more than they bargained for…
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Using a sophisticated nanotechnology-based “vaccine,” researchers were able to successfully cure mice with type 1 diabetes and slow the onset of the disease in mice at risk for the disease…
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Using gene therapy, researchers in the US managed to reverse Type 1 diabetes in laboratory mice, raising hope that a “cure” for the disease might be developed using this approach. However, only about 50 per cent of the treated mice responded to the therapy, so there is still a lot of work to do before such a method can be trialled as a...
A new understanding of insulin resistance and the action of diabetes drugs such as Avandia and Actos could pave the way for improved medications that are more selective and safer, say scientists from Dana-Farber Cancer Institute and The Scripps Research Institute…
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Oramed Pharmaceuticals Inc. (OTCBB: ORMP.OB), a developer of alternative drug delivery systems, announced that the paper entitled, “Open-label study to assess the safety and pharmacodynamics of five oral insulin formulations in healthy subjects,” authored by Dr. Roy Eldor, Dr. Miriam Kidron and Dr. Ehud Arbit, was accepted and published...
People who have a family predisposition to Type 2 diabetes may be more likely to gain weight after overeating than those without a family diabetes link.
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A new study by Johns Hopkins researchers has found that insulin, the sugar-regulating hormone, is required for normal bone development and that it may provide a link between bone health and metabolic disease, such as diabetes. The study, headed by Thomas Clemens, Ph.D…
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Individuals with a family history of diabetes type 2 who overeat for a specific period put on more weight than other people of the same age and lifestyle who overeat to the same extent. In other words, short-term overeating results in more weight gain for people with a genetic predisposition to diabetes type 2…
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